Serum Antibody Opsonic Activity against Actinobacillus actinomycetemcomitans in Human Periodontal Diseases
作者： K. Underwood , K. Sjostrom , R. Darveau , R. Lamont , H. Schenkein
DOI: 10.1093/INFDIS/168.6.1436
关键词:
摘要: Actinobacillus actinomycetemcomitans is frequently associated with severe periodontitis. Many periodontitis patients have elevated levels of serum IgG antibodies to A. actinomycetemcomitans, but the role these unknown. This study evaluated functional capacity anti-A. antibody enhance phagocytosis by polymorphonuclear leukocytes. Chemoluminescence assays were done using sera from 64 subjects, 61 whom had periodontitis; results compared subject's titer and avidity. There was a strong correlation between chemoluminescence log (P < .00001) weak avidity .05). The support hypothesis that are important in promoting killing actinomycetemcomitans. Subjects who develop high highly avid against may greater resistance continued or repeated infection this pathogen.
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