Estimating the net effect of unmeasured ions in human extracellular fluid using a new mathematical model. Part II: Practical issues.

摘要: Building on the theoretical considerations developed in Part I of this two-part series, a population range was established for new extracellular fluid acid-base parameter using Monte Carlo simulation. This unmeasured ion excess, had normal +/- 2.50 mEq/l which slightly narrower than standard base excess at 3.20 mmol/l. In both cases, most variation occurred as result estimation bicarbonate concentration. Finally, several short clinical vignettes were explored to highlight differences between and excess.