Strong ion calculator--a practical bedside application of modern quantitative acid-base physiology.

摘要: Objective To review acid-base balance by considering the physical effects of ions in solution and describe use a calculator to derive strong ion difference Atot gap. Data sources A articles reporting on interpretation acid base balance. Summary Tremendous progress has been made last decade our understanding physiology. We now have quantitative mechanisms underlying acidity an aqueous solution. can predict given information about concentration various ion-forming species within it. changes status caused disturbance these factors, finally, we detect unmeasured anions with greater sensitivity than was previously possible anion gap, using either arterial or venous blood sampling. Acid-base ceased be intuitive arcane art. Much it is exact computation that automated incorporated into online hospital laboratory system. Conclusions All diseases all therapies affect patient's only through final common pathway one more three independent factors. With Constable's equations accurately plasma. When there discrepancy between observed predicted deduce net account for difference.