Antidiarrhoeal activity of leaf extract of celosia argentea in experimentally induced diarrhoea in rats.

摘要: In order to scientifically apprise some of the anecdotal, folkloric, ethno medical uses celosia argentea, present study was undertaken examine antidiarrhoeal properties alcoholic extract leaves Celosia argentea on diarrhoea by using different experimental models. Anti-diarrhoeal effect evaluated castor oil induced diarrhoea, charcoal meal test and PGE 2 diarrhoea. Loperamide (2 mg/kg) atropine (0.1mg/kg) were used as standard drugs. Extract in 100 200 mg/kg dose. It produced dose related anti-diarrhoeal effect. Results suggest that it may act centrally inhibit PGE2 give effects. Result also suggests its anti-muscarinic activity.