Catastrophic costs potentially averted by tuberculosis control in India and South Africa: a modelling study.

摘要: Summary Background The economic burden on households affected by tuberculosis through costs to patients can be catastrophic. WHO's End TB Strategy recognises and aims eliminate these potentially devastating effects. We assessed whether aggressive expansion of services might reduce catastrophic costs. Methods estimated the reduction in tuberculosis-related with an India South Africa from 2016 2035, line Strategy. Using modelled incidence mortality for patient-incurred cost estimates, we investigated three intervention scenarios: improved treatment drug-sensitive tuberculosis; multidrug-resistant access care intensified case finding (South only). defined as sum direct medical, non-medical, indirect exceeding 20% total annual household income. Intervention effects were quantified changes number incurring quintiles Findings In Africa, improvements could 6–19%. benefits would greatest poorest households. expanded decrease 5–20%, but gains seen largely after 5–10 years. Interpretation Aggressive lessen, although not eliminate, financial Funding Bill & Melinda Gates Foundation.