Directed Evolution and Genomic Analysis of Novel Yeast Species for More Efficient Biomass Conversion
作者： Gavin Sherlock , Katja Schwartz , R. P. Levine , Barbara L. Dunn , R. Frank Rosenzweig
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摘要: We propose to develop novel, adaptively evolved, hybrid yeast strains having phenotypes that enhance the efficiency of industrial-scale biomass conversion. Specifically, we heat- and ethanol-tolerant convert both xylose glucose ethanol, studying key aspects their functional systems biology as they evolve. Initially, will increase amount standing genetic variation upon which natural selection can act, by hybridizing species in
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