摘要: The status and potential functions of taurine in the retina have been reviewed. Taurine is present high concentrations all species tested, while retinal enzymes necessary to synthesize are presumed vary among those species. documented low activity cysteinesulfinic acid decarboxylase, a key enzyme biosynthesis, livers cat, monkey human possibly reflect their retinas, indicating reliance on diet as an important source taurine. Both high- low-affinity binding proteins uptake systems described for tissue. Evoked release by light other depolarizing stimuli well documented. Retinal pathologies including diminished ERGs morphologic changes reported animals man deficient Possible include: (1) protection photoreceptor - based shielding effects rod outer segments exposed chemicals; (2), regulation Ca2+ transport modulatory fluxes presence absence ATP; (3) signal transduction inhibitory protein phosphorylation.
elsevier.com
sci-hub.se 参考文章(243)
John A. Sturman, Kenneth C. Hayes, The Biology of Taurine in Nutrition and Development Springer, Boston, MA. pp. 231- 299 ,(1980) , 10.1007/978-1-4757-4448-4_9
Kinya Kuriyama, Shuji Ida, Chihiro Nishimura, Differential Effects of Light and Dark Adaptations on Function and Metabolism of Retinal Taurine and γ-Aminobutyric Acid (GABA) Advances in Experimental Medicine and Biology. ,vol. 139, pp. 221- 238 ,(1982) , 10.1007/978-1-4757-0402-0_15
E L Berson, S Y Schmidt, C Huang, G Watson, Retinal degeneration in cats fed casein. III. Taurine deficiency and ERG amplitudes. Investigative Ophthalmology & Visual Science. ,vol. 16, pp. 673- 678 ,(1977)
Charles E. Wright, Harris H. Tallan, Tena R. Wright, Bruce Gillam, Gerald E. Gaull, John A. Sturman, Taurine Availability and Function in Neurogenetic Retinopathies Advances in Experimental Medicine and Biology. ,vol. 217, pp. 101- 112 ,(1987) , 10.1007/978-1-4899-0405-8_10
E L Berson, S Y Schmidt, K C Hayes, Retinal degeneration in cats fed casein. I. Taurine deficiency. Investigative Ophthalmology & Visual Science. ,vol. 15, pp. 47- 52 ,(1976)
S Y Schmidt, G D Aguirre, Reductions in taurine secondary to photoreceptor loss in Irish setters with rod-cone dysplasia. Investigative Ophthalmology & Visual Science. ,vol. 26, pp. 679- 683 ,(1985)
M. J. Voaden, A. C. I. Oraedu, J. Marshall, N. Lake, Taurine in the Retina The Effects of Taurine on Excitable Tissues. pp. 145- 160 ,(1981) , 10.1007/978-94-009-8093-8_13
E L Berson, A R Rabin, S Y Schmidt, G Watson, K C Hayes, Retinal degeneration in cats fed casein. II. Supplementation with methionine, cysteine, or taurine. Investigative Ophthalmology & Visual Science. ,vol. 15, pp. 52- 58 ,(1976)
Radovan Kubiek, Antonn Dolnek, Taurine et acides aminés dans la rétine des animaux Journal of Chromatography A. ,vol. 1, pp. 266- 268 ,(1958) , 10.1016/S0021-9673(00)93422-8
K C Hayes, H M Wisniewski, G Y Wen, A C Cornwell, A A Lidsky, J A Sturman, Tapetum disorganization in taurine-depleted cats. Investigative Ophthalmology & Visual Science. ,vol. 18, pp. 1200- 1206 ,(1979)