Electronic Cigarette: Role in the Primary Prevention of Oral Cavity Cancer
作者： Teresa Franco , Serena Trapasso , Lidia Puzzo , Eugenia Allegra
DOI: 10.4137/CMENT.S40364
关键词:
摘要: Background: Cigarette smoke has been identified as the main cause of oral cavity carcinoma. Recently, electronic cigarette, a battery-operated device, was developed to help smokers stop their tobacco addiction. This study aimed evaluate safety cigarettes and establish possible role such device in primary prevention cancer. Subjects Methods: included 65 subjects who were divided into three groups (smokers, e-cigarette smokers, nonsmokers). All submitted cytologic examination by scraping mucosa. The slides microscopically evaluated through micronucleus assay test. Results: prevalence micronuclei significantly decreased smoker group. There no statistically significant differences distribution according type gender, age. Conclusions: use seems be safe for cells should suggested an aid smoking cessation.
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sci-hub.se 参考文章(32)
F. Baudi, A. Garozzo, E. Allegra, F. Fagiani, F.S. Costanzo, A. La Boria, Multiple head and neck tumours and their genetic relationship. Acta Otorhinolaryngologica Italica. ,vol. 29, pp. 237- 241 ,(2009)
A Garozzo, L. Puzzo, E Allegra, N Lombardo, The usefulness of toluidine staining as a diagnostic tool for precancerous and cancerous oropharyngeal and oral cavity lesions. Acta Otorhinolaryngologica Italica. ,vol. 29, pp. 187- 190 ,(2009)
Nicholas McQueen, Erin J. Partington, Kathleen F. Harrington, Eben L. Rosenthal, William R. Carroll, Cecelia E. Schmalbach, Smoking Cessation and Electronic Cigarette Use among Head and Neck Cancer Patients Otolaryngology-Head and Neck Surgery. ,vol. 154, pp. 73- 79 ,(2016) , 10.1177/0194599815613279
Hayley Born, Michael Persky, Dennis H. Kraus, Robert Peng, Milan R. Amin, Ryan C. Branski, Electronic Cigarettes A Primer for Clinicians Otolaryngology-Head and Neck Surgery. ,vol. 153, pp. 5- 14 ,(2015) , 10.1177/0194599815585752
N. Agrawal, M. J. Frederick, C. R. Pickering, C. Bettegowda, K. Chang, R. J. Li, C. Fakhry, T.-X. Xie, J. Zhang, J. Wang, N. Zhang, A. K. El-Naggar, S. A. Jasser, J. N. Weinstein, L. Trevino, J. A. Drummond, D. M. Muzny, Y. Wu, L. D. Wood, R. H. Hruban, W. H. Westra, W. M. Koch, J. A. Califano, R. A. Gibbs, D. Sidransky, B. Vogelstein, V. E. Velculescu, N. Papadopoulos, D. A. Wheeler, K. W. Kinzler, J. N. Myers, Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1 Science. ,vol. 333, pp. 1154- 1157 ,(2011) , 10.1126/SCIENCE.1206923
Saman Warnakulasuriya, Global epidemiology of oral and oropharyngeal cancer Oral Oncology. ,vol. 45, pp. 309- 316 ,(2009) , 10.1016/J.ORALONCOLOGY.2008.06.002
Chuang ShuChun Chuang ShuChun, G Scelo, JM Tonita, S Tamaro, JG Jonasson, EV Kliewer, K Hemminki, E Weiderpass, E Pukkala, E Tracey, S Friis, V Pompe-Kirn, DH Brewster, C Martos, Chia KeeSeng Chia KeeSeng, P Boffetta, P Brennan, M Hashibe, Risk of second primary cancer among patients with head and neck cancers: A pooled analysis of 13 cancer registries International Journal of Cancer. ,vol. 123, pp. 2390- 2396 ,(2008) , 10.1002/IJC.23798
B. A. King, R. Patel, K. H. Nguyen, S. R. Dube, Trends in Awareness and Use of Electronic Cigarettes Among US Adults, 2010–2013 Nicotine & Tobacco Research. ,vol. 17, pp. 219- 227 ,(2015) , 10.1093/NTR/NTU191
Kiran Jadhav, Nidhi Gupta, BR Ahmed Mujib, Micronuclei: An essential biomarker in oral exfoliated cells for grading of oral squamous cell carcinoma. Journal of Cytology. ,vol. 28, pp. 7- 12 ,(2011) , 10.4103/0970-9371.76941
W. Schmid, The micronucleus test. Mutation Research\/environmental Mutagenesis and Related Subjects. ,vol. 31, pp. 9- 15 ,(1975) , 10.1016/0165-1161(75)90058-8