Compliance of pediatric and adolescent cancer patients

摘要: Compliance with self-administered therapy in pediatric and adolescent patients is not always complete. Noncompliance may result erroneous conclusions about the efficacy of a given lead to unnecessary tests alteration treatment regimens. To examine causes noncompliance, 46 cancer aged 2.5 23 years (mean age, 6.85 years) 40 parents were extensively interviewed at 2 weeks, 20 50 weeks post-diagnosis. The results self-reported compliance corroborated by serum bioassay prescribed medications. A significant correlation between age patient chemotherapeutic agents nonchemotherapeutic medications was found (P less than 0.05 P 0.02, respectively), being compliant often. Over course therapy, among decreased, but significantly. negative number children family. Compliers noncompliers did differ significantly how well they understood instructions concerning take their medication = 0.04). No correlations stage disease, or type drugs used, complexity regimen, degree satisfaction information patient, understanding treatment, belief found. main reasons for noncompliance forgetfulness, busy schedules, nonavailability medication. More compliers agreement regarding who responsible administration complex multifaceted issue which interrelates large medical social factors.