PCpheno: assessing the role cellular organizational units in determining phenotype
作者： Nolwenn Le Meur , Robert Gentleman
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摘要: We propose computational methods and statistical paradigms to explore the relationships between phenotypic data cellular organizational units, such as multi-protein complexes or pathways. Indeed, while proteins are often primary unit used by cells carry out many different functions that cell requires for life, they seldom accomplish important tasks alone, but rather assemble into units. Recent studies suggest some control of phenotype can be usefully attributed than genes (Deutschbauer et al., 2005; Spirin 2006) hence may help provide elucidation underlying roles mechanisms directly changes in phenotype.
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