Epidemiology and clinical impact of hepatitis D virus (delta) infection

作者: Ira M. Jacobson , Jules L. Dienstag , Barbara G. Werner , Doreen B. Brettler , Peter H. Levine

DOI: 10.1002/HEP.1840050205

关键词:

摘要: We tested sera collected between 1976 and 1984 from 362 persons in a variety of epidemiologic categories with acute chronic hepatitis B 76 hemophiliacs drug addicts antibodies for D markers. Hepatitis markers were common hemophiliacs, addicts, Afghanistanis, prisoners hemodialysis patients; rare other hepatitis-B endemic areas, sporadic homosexual men; absent health-care workers institutionalized mentally retarded persons. No change was observed the frequency this infection during 9 years study. found 5% patients B, 1 3 fulminant 4 (1 male) 12 episodes carriers. more frequent liver disease (18%) than asymptomatic carriage (2%), but there no association severity D. These findings indicate that, to date, have been spared agent suggest that males may not continue be spared. Even an area nonendemic D, contributed 20 30% superimposed on infection.

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