Ultrastructural abnormalities of the carotid body in sudden infant death syndrome.

摘要: The carotid bodies of four infants who died sudden infant death syndrome (SIDS) were compared, using electron microscopic techniques, with the various control subjects. In SIDS patients, there was a marked reduction or absence dense cytoplasmic granules chemorecptor cells, as well in cell number and size. These ultrastructural abnormalities may be pathophysiologically related to SIDS. A defect this respiratory organ could block normal stimulation respiration during periods hypoxia that occur episodes sleep apnea infancy. Further studies by microscopy are required confirm degranulation body pathognomonic sign Screening high-risk should directed at studying its mediated responses hypoxia.