The DNA Repair Protein OGG1 Protects Against Obesity by Altering Mitochondrial Energetics in White Adipose Tissue.

作者: Sai Santosh Babu Komakula , Jana Tumova , Deeptha Kumaraswamy , Natalie Burchat , Vladimir Vartanian

DOI: 10.1038/S41598-018-33151-1

关键词:

摘要: … changes in mitochondrial genes and proteins translate to alterations in mitochondrial function, we measured O 2 consumption in eWAT punches from chow-fed mice using a Seahorse …

参考文章(69)
Mateusz Dezor, Jolanta Dorszewska, Wojciech Kozubski, Joanna Jaroszewska-Kolecka, Bartosz Kempisty, Robert Bugaj, Agata Rozycka, Anna Polrolniczak, Jolanta Florczak, Paweł P Jagodzinski, Expression of 8-oxoguanine DNA glycosylase 1 (OGG1) and the level of p53 and TNF-αlpha proteins in peripheral lymphocytes of patients with Alzheimer's disease. Folia Neuropathologica. ,vol. 49, pp. 123- 131 ,(2011)
Kenichi Nishioka, Toshio Ohtsubo, Hisanobu Oda, Toshiyuki Fujiwara, Dongchon Kang, Keizo Sugimachi, Yusaku Nakabeppu, Expression and Differential Intracellular Localization of Two Major Forms of Human 8-Oxoguanine DNA Glycosylase Encoded by Alternatively Spliced OGG1 mRNAs Molecular Biology of the Cell. ,vol. 10, pp. 1637- 1652 ,(1999) , 10.1091/MBC.10.5.1637
V. Panduri, G. Liu, S. Surapureddi, J. Kondapalli, S. Soberanes, N.C. de Souza-Pinto, V.A. Bohr, G.R.S. Budinger, P.T. Schumacker, S.A. Weitzman, D.W. Kamp, Role of mitochondrial hOGG1 and aconitase in oxidant-induced lung epithelial cell apoptosis Free Radical Biology and Medicine. ,vol. 47, pp. 750- 759 ,(2009) , 10.1016/J.FREERADBIOMED.2009.06.010
Mohammad Jamaluddin, Shaofei Wang, Istvan Boldogh, Bing Tian, Allan R. Brasier, TNF-α-induced NF-κB/RelA Ser276 phosphorylation and enhanceosome formation is mediated by an ROS-dependent PKAc pathway Cellular Signalling. ,vol. 19, pp. 1419- 1433 ,(2007) , 10.1016/J.CELLSIG.2007.01.020
Makoto Daimon, Toshihide Oizumi, Sayumi Toriyama, Shigeru Karasawa, Yumi Jimbu, Kiriko Wada, Wataru Kameda, Shinji Susa, Masaaki Muramatsu, Isao Kubota, Sumio Kawata, Takeo Kato, Association of the Ser326Cys polymorphism in the OGG1 gene with type 2 DM Biochemical and Biophysical Research Communications. ,vol. 386, pp. 26- 29 ,(2009) , 10.1016/J.BBRC.2009.05.119
Harini Sampath, Vladimir Vartanian, M. Rick Rollins, Kunihiko Sakumi, Yusaku Nakabeppu, R. Stephen Lloyd, 8-Oxoguanine DNA Glycosylase (OGG1) Deficiency Increases Susceptibility to Obesity and Metabolic Dysfunction PLoS ONE. ,vol. 7, pp. e51697- ,(2012) , 10.1371/JOURNAL.PONE.0051697
Marc Liesa, Orian S. Shirihai, Mitochondrial dynamics in the regulation of nutrient utilization and energy expenditure. Cell Metabolism. ,vol. 17, pp. 491- 506 ,(2013) , 10.1016/J.CMET.2013.03.002
Tamar Paz-Elizur, Ziv Sevilya, Yael Leitner-Dagan, Dalia Elinger, Laila C. Roisman, Zvi Livneh, DNA repair of oxidative DNA damage in human carcinogenesis: Potential application for cancer risk assessment and prevention Cancer Letters. ,vol. 266, pp. 60- 72 ,(2008) , 10.1016/J.CANLET.2008.02.032