The polymorphisms of bovine VEGF gene and their associations with growth traits in Chinese cattle.
作者： Yonghong Pang , Juqiang Wang , Chunlei Zhang , Chuzhao Lei , Xianyong Lan
DOI: 10.1007/S11033-010-0163-6
关键词:
摘要: PCR-SSCP and DNA sequencing methods were employed to screen the genetic variation of VEGF gene in 671 individuals belonging three Chinese indigenous cattle breeds including Nanyang, Jiaxian Red Qinchuan. Three haplotypes (A, B C), four observed genotypes (AA, AB, BB AC) new SNPs (6765T>C ss130456744, 6860A>G ss130456745, 6893T>C ss130456746) detected. The analysis suggested that one SNP (ss130456744) bovine had significant effects on birth weight, body weight heart girth at 6 months old Nanyang breed (P < 0.05). results showed intron 2 is associated with early development growth cattle. These findings raise hope this polymorphism can be a molecular breeding marker strategies through assisted selection (MAS) domestic
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sci-hub.se 参考文章(21)
M. D. MacNeil, M. D. Grosz, Genome-wide scans for QTL affecting carcass traits in Hereford x composite double backcross populations. Journal of Animal Science. ,vol. 80, pp. 2316- 2324 ,(2002) , 10.2527/2002.8092316X
Q. Zhao, M. E. Davis, H. C. Hines, Associations of polymorphisms in the Pit-1 gene with growth and carcass traits in Angus beef cattle. Journal of Animal Science. ,vol. 82, pp. 2229- 2233 ,(2004) , 10.2527/2004.8282229X
Heping Cao, Joseph F. Urban, Richard A. Anderson, Insulin increases tristetraprolin and decreases VEGF gene expression in mouse 3T3-L1 adipocytes. Obesity. ,vol. 16, pp. 1208- 1218 ,(2008) , 10.1038/OBY.2008.65
Napoleone Ferrara, None, VEGF and the quest for tumour angiogenesis factors Nature Reviews Cancer. ,vol. 2, pp. 795- 803 ,(2002) , 10.1038/NRC909
Napoleone Ferrara, Terri Davis-Smyth, THE BIOLOGY OF VASCULAR ENDOTHELIAL GROWTH FACTOR Endocrine Reviews. ,vol. 18, pp. 4- 25 ,(1997) , 10.1210/EDRV.18.1.0287
Xinsheng Lai, Xianyong Lan, Hong Chen, Xinlei Wang, Keyi Wang, Mou Wang, Hui Yu, Miao Zhao, A novel SNP of the Hesx1 gene in bovine and its associations with average daily gain Molecular Biology Reports. ,vol. 36, pp. 1677- 1681 ,(2009) , 10.1007/S11033-008-9368-3
Kari Alitalo, Tuomas Tammela, Tatiana V. Petrova, Lymphangiogenesis in development and human disease Nature. ,vol. 438, pp. 946- 953 ,(2005) , 10.1038/NATURE04480
Napoleone Ferrara, Hans-Peter Gerber, Jennifer LeCouter, None, The biology of VEGF and its receptors. Nature Medicine. ,vol. 9, pp. 669- 676 ,(2003) , 10.1038/NM0603-669
Hairong Peng, Arvydas Usas, Anne Olshanski, Andrew M Ho, Brian Gearhart, Gregory M Cooper, Johnny Huard, VEGF improves, whereas sFlt1 inhibits, BMP2-induced bone formation and bone healing through modulation of angiogenesis. Journal of Bone and Mineral Research. ,vol. 20, pp. 2017- 2027 ,(2005) , 10.1359/JBMR.050708
Chun-Lei Zhang, Yan-Hong Wang, Hong Chen, Xian-Yong Lan, Chu-Zhao Lei, Xing-Tang Fang, Association between variants in the 5′-untranslated region of the bovine MC4R gene and two growth traits in Nanyang cattle Molecular Biology Reports. ,vol. 36, pp. 1839- 1843 ,(2009) , 10.1007/S11033-008-9388-Z