Fate of the fish pathogen Aeromonas salmonicida in the peritoneal cavity of rainbow trout.

摘要: A model was developed to study the fate of fish pathogen Aeromonas salmonicida in vivo, inside a specialized intraperitoneal chamber implanted rainbow trout, Oncorhynchus mykiss. Although normally recalcitrant lytic agents vitro, owing presence its regular surface array (S layer), A. rapidly killed peritoneal cavity by host-derived, soluble activity present fluid. Peritoneal fluid also found kill other bacteria and lyse various types erythrocytes, but particularly salmonicida. Intraperitoneal survival injected (free) cells several orders magnitude higher than (restrained) cells. Injected free could evade because they readily spread, initiating lethal infections. One evasion strategy envisioned be penetration (or) tissue macrophages. In spite killing mechanisms these phagocytic cells, ...