Hyperthermia induced by transient receptor potential vanilloid-1 (TRPV1) antagonists in human clinical trials: Insights from mathematical modeling and meta-analysis
作者： Andras Garami , Yury P Shimansky , Zoltan Rumbus , Robson CL Vizin , Nelli Farkas
DOI: 10.1016/J.PHARMTHERA.2020.107474
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摘要: … TRPV1 drives thermoeffectors by mediating pH signals from the trunk, but not T b signals, our analysis suggests that TRPV1 … Hence, in humans (but not in rats), TRPV1 is likely to serve …
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