Role of estrogen receptor- α in an experimental model of bronchial asthma.
作者： Saloni Shah , Priyanshee V. Gohil , Gaurang Shah , None
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摘要: Background:Use of hormone replacement therapy (HRT) may increase the risk adult -onset asthma in women. Variousin vitrostudies have reported that estradiol stimulates human mast cell lines causing release allergic mediators which was not observed estrogenreceptor-�±(ER-�±) knockout mice.Thus,estrogen might be a key element occurrence asthma. In present s tudy, we proposed t o determine role ER-�± anexperimental model bronchial Methods:Trypsin and eggalbumin induced chronic w ereused. Onthe28 th day, various parameters such as pO
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