Prognostic and Therapeutic Implications of EGFR and KRAS Mutations in Resected Lung Adenocarcinoma

作者: Jenifer L. Marks , Stephen Broderick , Qin Zhou , Dhananjay Chitale , Allan R. Li

DOI: 10.1097/JTO.0B013E318160C607

关键词:

摘要: … lung adenocarcinomas shows that EGFR and KRAS mutations delineate biologically distinct subsets of lung adenocarcinoma… patients whose tumors contain an EGFR mutation had a 90…

参考文章(32)
Anne S. Tsao, Xi Ming Tang, Bradley Sabloff, Lianchun Xiao, Hisayuki Shigematsu, Jack Roth, Margaret Spitz, Waun Ki Hong, Adi Gazdar, Ignacio Wistuba, Clinicopathologic Characteristics of the EGFR Gene Mutation in Non–small Cell Lung Cancer Journal of Thoracic Oncology. ,vol. 1, pp. 231- 239 ,(2006) , 10.1016/S1556-0864(15)31573-2
Sjoerd Rodenhuis, Robert J. C. Slebos, Clinical significance of ras oncogene activation in human lung cancer. Cancer Research. ,vol. 52, pp. 2665- 2669 ,(1992)
J. P. Pignon, H. Tribodet, G. V. Scagliotti, J. Y. Douillard, F. A. Shepherd, R. J. Stephens, T. Le Chevalier, Lung Adjuvant Cisplatin Evaluation (LACE): A pooled analysis of five randomized clinical trials including 4,584 patients Journal of Clinical Oncology. ,vol. 24, pp. 7008- 7008 ,(2006) , 10.1200/JCO.2006.24.18_SUPPL.7008
S Rodenhuis, L Boerrigter, B Top, R J Slebos, W J Mooi, L van't Veer, N van Zandwijk, Mutational activation of the K-ras oncogene and the effect of chemotherapy in advanced adenocarcinoma of the lung: a prospective study. Journal of Clinical Oncology. ,vol. 15, pp. 285- 291 ,(1997) , 10.1200/JCO.1997.15.1.285
Adi F. Gazdar, Shinichi Toyooka, Kazunori Tsukuda, Mitsune Tanimoto, Masahiro Tabata, Kouichi Ichimura, Masaaki Yano, Toshihide Tsuda, Hisayuki Shigematsu, Hiroshi Date, Kunitoshi Tomii, Nobuyoshi Shimizu, Hiroshi Ueoka, Motoi Aoe, Masaki Tokumo, Katsuyuki Kiura, The Relationship between Epidermal Growth Factor Receptor Mutations and Clinicopathologic Features in Non–Small Cell Lung Cancers Clinical Cancer Research. ,vol. 11, pp. 1167- 1173 ,(2005)
Qiulu Pan, William Pao, Marc Ladanyi, Rapid Polymerase Chain Reaction-Based Detection of Epidermal Growth Factor Receptor Gene Mutations in Lung Adenocarcinomas The Journal of Molecular Diagnostics. ,vol. 7, pp. 396- 403 ,(2005) , 10.1016/S1525-1578(10)60569-7
Sjoerd Rodenhuis, Robert J. C. Slebos, TherasOncogenes in Human Lung Cancer American Review of Respiratory Disease. ,vol. 142, pp. S27- S30 ,(1990) , 10.1164/AJRCCM/142.6_PT_2.S27
C Mascaux, N Iannino, B Martin, M Paesmans, T Berghmans, M Dusart, A Haller, P Lothaire, A-P Meert, S Noel, J-J Lafitte, J-P Sculier, The role of RAS oncogene in survival of patients with lung cancer: a systematic review of the literature with meta-analysis British Journal of Cancer. ,vol. 92, pp. 131- 139 ,(2005) , 10.1038/SJ.BJC.6602258
Jenifer L. Marks, Michael D. McLellan, Maureen F. Zakowski, Alex E. Lash, Yumi Kasai, Stephen Broderick, Inderpal S. Sarkaria, DuyKhanh Pham, Bhuvanesh Singh, Tracie L. Miner, Ginger A. Fewell, Lucinda L. Fulton, Elaine R. Mardis, Richard K. Wilson, Mark G. Kris, Valerie W. Rusch, Harold Varmus, William Pao, Mutational Analysis of EGFR and Related Signaling Pathway Genes in Lung Adenocarcinomas Identifies a Novel Somatic Kinase Domain Mutation in FGFR4 PLOS ONE. ,vol. 2, ,(2007) , 10.1371/JOURNAL.PONE.0000426