Contradictory Effects of NLRP3 Inflammasome Regulatory Mechanisms in Colitis.

作者: Kohei Wagatsuma , Hiroshi Nakase

DOI: 10.3390/IJMS21218145

关键词:

摘要: … colitis-induced lung inflammation via the NLRP3 inflammasome [33]. Kynurenic acid/GPR35 axis limits NLRP3 inflammasome activation and exacerbates colitis in … suggest that NLRP3 …

参考文章(155)
Takashi Shichita, Akihiko Yoshimura, Minako Ito, Rimpei Morita, Yoshiko Noguchi, Ritsuko Komine, Masahiro Okada, Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury Nature Communications. ,vol. 6, pp. 7360- 7360 ,(2015) , 10.1038/NCOMMS8360
Francesco Trapasso, Tiziana Parrello, Livia Biancone, Rodolfo Iuliano, Giovanni Monteleone, Alfredo Fusco, Antonella Stella, Francesco Luzza, Francesco Pallone, Bioactive IL-18 expression is up-regulated in Crohn's disease. Journal of Immunology. ,vol. 163, pp. 143- 147 ,(1999)
Samuel Huber, Nicola Gagliani, Richard A. Flavell, Life, death, and miracles: Th17 cells in the intestine. European Journal of Immunology. ,vol. 42, pp. 2238- 2245 ,(2012) , 10.1002/EJI.201242619
Fabio Martinon, Kimberly Burns, Jürg Tschopp, The Inflammasome Molecular Cell. ,vol. 10, pp. 417- 426 ,(2002) , 10.1016/S1097-2765(02)00599-3
Stefan Wirtz, Christoph Becker, Richard Blumberg, Peter R. Galle, Markus F. Neurath, Treatment of T Cell-Dependent Experimental Colitis in SCID Mice by Local Administration of an Adenovirus Expressing IL-18 Antisense mRNA Journal of Immunology. ,vol. 168, pp. 411- 420 ,(2002) , 10.4049/JIMMUNOL.168.1.411
Franz Bauernfeind, Eva Bartok, Anna Rieger, Luigi Franchi, Gabriel Núñez, Veit Hornung, Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome Journal of Immunology. ,vol. 187, pp. 613- 617 ,(2011) , 10.4049/JIMMUNOL.1100613
F Cominelli, TT Pizarro, Interleukin-1 and interleukin-1 receptor antagonist in inflammatory bowel disease. Alimentary Pharmacology & Therapeutics. ,vol. 10, pp. 49- 53 ,(1996) , 10.1046/J.1365-2036.1996.22164020.X
Stephen J. Bickston, Fabio Cominelli, Marcia Bentz, Theresa T. Pizarro, Christopher A. Moskaluk, Michael F. Smith, Miette H. Michie, Jan Woraratanadharm, Eugene Foley, IL-18, a Novel Immunoregulatory Cytokine, Is Up-Regulated in Crohn’s Disease: Expression and Localization in Intestinal Mucosal Cells Journal of Immunology. ,vol. 162, pp. 6829- 6835 ,(1999)
Nobuhiko Kayagaki, Irma B. Stowe, Bettina L. Lee, Karen O’Rourke, Keith Anderson, Søren Warming, Trinna Cuellar, Benjamin Haley, Merone Roose-Girma, Qui T. Phung, Peter S. Liu, Jennie R. Lill, Hong Li, Jiansheng Wu, Sarah Kummerfeld, Juan Zhang, Wyne P. Lee, Scott J. Snipas, Guy S. Salvesen, Lucy X. Morris, Linda Fitzgerald, Yafei Zhang, Edward M. Bertram, Christopher C. Goodnow, Vishva M. Dixit, Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling Nature. ,vol. 526, pp. 666- 671 ,(2015) , 10.1038/NATURE15541