Body Mass Index, Weight Change, and Risk of Mobility Disability in Middle-aged and Older Women: The Epidemiologic Follow-up Study of NHANES I

摘要: Objective. —As disability is highly prevalent among older women, costly, and affects the quality of life, preventable causes must be identified. In this study, we investigated relationship between body mass index (BMI), weight change, onset in women. Design. —Prospective cohort study. Setting. —The nationally representative US epidemiologic follow-up study National Health Nutrition Examination Survey (NHANES) I (1971 through 1987). Patients. —White women classified as young-old (mean age 60 years at baseline, mean 65 follow-up) old-old 76 80 follow-up). Main Outcome Measures. relative odds for mobility associated with tertiles past BMI (measured 8 to 16 prior ascertainment) current 2 5 change two measurements. Results. —In both cohorts, high group (>27 >28.1 cohort) had a twofold increase risk compared low group. High was strongly related women; it not strong predictor only, who experienced loss more than 5% weight-stable These results were adjusted age, smoking, education, time importantly modified addition into models single or multiple health conditions. Conclusions. —These prospective data suggest that long-term persists even very old age. However, paradoxical requires further Programs prevent overweight may have potential decreasing (JAMA. 1994;271:1093-1098)