作者: O. Friedman , Y. Shukla , A. G. Logan
DOI: 10.1038/AJH.2009.165
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摘要: BACKGROUND Abnormalities in sleep duration and circadian blood pressure (BP) rhythm are both independently associated with increased risk of death cardiovascular disease. The relationship, however, between these two entities remains unclear.This study was undertaken to determine whether abnormal is nondipping status elevated morning surge. METHODS In a cross-sectional study, we assessed the relationship self-reported BP profiles from 24-h ambulatory monitoring (ABPM) 108 normotensive 417 hypertensive subjects, independent relevant sociodemographic, anthropometric, medical factors. RESULTS On average, subjects reported sleeping 6.5 ± 1.7 h 18.5% ≤5 7.6%, ≥9 h. There were 199 (37.9%) nondippers our cohort mean surge 18.7 mm Hg. adjusted odds ratio for (<10% nocturnal systolic fall) 1-h decrement 1.12 (P = 0.04) age per 5-year increment, 1.15 0.0003). an (≥18.0 Hg) increment 1.13 0.02). CONCLUSIONS Our indicates that deficit decreased surge, whereas surfeit less These findings provide possible link heightened disease disturbances extremes quantity.