Bioimpedance-derived differences in cardiac physiology during exercise stress testing in low-risk chest pain patients.

摘要: BACKGROUND Little has been written about the utility of thoracic electrical bioimpedance (TEB)-derived cardiac physiologic variables in evaluating patients with low-risk chest pain syndromes. Noninvasive can monitor physiology while a patient is performing an exercise stress test. In addition, demographics pain, incidence coronary artery disease (CAD), and methods used for evaluation have well-documented sex differences. OBJECTIVE The objectives are to show that there different responses test Chest Pain Evaluation Unit without true CAD could be stratify difference TEB results. METHODS Patients 18 65 years age were eligible. attached throughout procedure. Heart rate (HR) was monitored. Primary dependent TEB-measured output (CO, L/min) stroke volume (SV, ml) at peak exercise. Secondary ejection fraction (%), end-diastolic (EDV, ml), ventricular time (ms), fluid index (omega) Outcome either proved or sex. by angiography, scintigraphy, echocardiogram. Results compared using Student's t assuming equal variances, significance considered P < 0.05, 95% confidence intervals calculated significant RESULTS Nine had CAD, 82 did not. Forty-three women 48 men included study. At exercise, significantly smaller increase EDV than (32.8 +/- 59.5 ml versus 89.3 101.8 change CO, SV, HR. CO SV EDV. CONCLUSION When trend toward same effect SV. Women increases men. Because no differences HR, HR as sole end point would miss these practical means measuring variables.