MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy.
作者： James Finke , Jennifer Ko , Brian Rini , Pat Rayman , Joanna Ireland
DOI: 10.1016/J.INTIMP.2011.01.030
关键词:
摘要: … GM-CSF's role in promoting MDSC survival in patient tumors … Additionally, persistence of MDSC also may be associated … Indeed our findings suggest that the most dominate MDSC …
elsevier.com
estranky.sk 参考文章(38)
Yongping Crawford, Napoleone Ferrara, None, Tumor and stromal pathways mediating refractoriness/resistance to anti-angiogenic therapies. Trends in Pharmacological Sciences. ,vol. 30, pp. 624- 630 ,(2009) , 10.1016/J.TIPS.2009.09.004
Anamika Bose, Jennifer L. Taylor, Sean Alber, Simon C. Watkins, Jorge A. Garcia, Brian I. Rini, Jennifer S. Ko, Peter A. Cohen, James H. Finke, Walter J. Storkus, Sunitinib facilitates the activation and recruitment of therapeutic anti-tumor immunity in concert with specific vaccination International Journal of Cancer. ,vol. 129, pp. 2158- 2170 ,(2011) , 10.1002/IJC.25863
Ge Ma, Johnny Kao, George X. Wang, Marcia Meseck, Max Sung, Myron Schwartz, Celia M. Divino, Ping-Ying Pan, Shu-Hsia Chen, Junko Ozao-Choy, The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies. Cancer Research. ,vol. 69, pp. 2514- 2522 ,(2009) , 10.1158/0008-5472.CAN-08-4709
Jennifer S. Ko, Arnold H. Zea, Brian I. Rini, Joanna L. Ireland, Paul Elson, Peter Cohen, Ali Golshayan, Patricia A. Rayman, Laura Wood, Jorge Garcia, Robert Dreicer, Ronald Bukowski, James H. Finke, Sunitinib Mediates Reversal of Myeloid-Derived Suppressor Cell Accumulation in Renal Cell Carcinoma Patients Clinical Cancer Research. ,vol. 15, pp. 2148- 2157 ,(2009) , 10.1158/1078-0432.CCR-08-1332
Jennifer S. Ko, Patricia Rayman, Joanna Ireland, Shadi Swaidani, Geqiang Li, Kevin D. Bunting, Brian Rini, James H. Finke, Peter A. Cohen, Direct and Differential Suppression of Myeloid-Derived Suppressor Cell Subsets by Sunitinib Is Compartmentally Constrained Cancer Research. ,vol. 70, pp. 3526- 3536 ,(2010) , 10.1158/0008-5472.CAN-09-3278
Dmitry I. Gabrilovich, Srinivas Nagaraj, Myeloid-derived suppressor cells as regulators of the immune system Nature Reviews Immunology. ,vol. 9, pp. 162- 174 ,(2009) , 10.1038/NRI2506
Maciej Kujawski, Marcin Kortylewski, Heehyoung Lee, Andreas Herrmann, Heidi Kay, Hua Yu, Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice. Journal of Clinical Investigation. ,vol. 118, pp. 3367- 3377 ,(2008) , 10.1172/JCI35213
Suzanne Ostrand-Rosenberg, Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity Cancer Immunology, Immunotherapy. ,vol. 59, pp. 1593- 1600 ,(2010) , 10.1007/S00262-010-0855-8
Luigi Dolcetti, Elisa Peranzoni, Stefano Ugel, Ilaria Marigo, Audry Fernandez Gomez, Circe Mesa, Markus Geilich, Gregor Winkels, Elisabetta Traggiai, Anna Casati, Fabio Grassi, Vincenzo Bronte, Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF European Journal of Immunology. ,vol. 40, pp. 22- 35 ,(2009) , 10.1002/EJI.200939903
Li Yang, Laura M. DeBusk, Koari Fukuda, Barbara Fingleton, Brenda Green-Jarvis, Yu Shyr, Lynn M. Matrisian, David P. Carbone, P.Charles Lin, Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis Cancer Cell. ,vol. 6, pp. 409- 421 ,(2004) , 10.1016/J.CCR.2004.08.031