Physical activity at age 12 and adult breast cancer risk (United States).

作者: Pamela M. Marcus , Beth Newman , Patricia G. Moorman , Robert C. Millikan , Donna Day Baird

DOI: 10.1023/A:1008971417282

关键词:

摘要: Objectives: Some epidemiologic studies suggest that adolescent physical activity reduces subsequent breast cancer risk. To examine this question further, we analyzed data on at age 12 had been collected as part of the Carolina Breast Cancer Study (CBCS). Methods: The CBCS is a population-based, case-control study 527 white and 337 African-American cases 790 controls, frequency-matched race. Respondents were asked whether, to what extent, they engaged in four specific activities (walking school, biking competitive training, performing vigorous household chores). Results: Women who reported participation any modest reduction risk (odds ratio (OR): 0.8, 95% confidence interval (CI): 0.6-1.0). Using an index measuring approximate number episodes per week, analyses revealed inverse relationships for nearly all levels relative no activity; weighting by metabolic equivalent scores produced similar results. Conclusions: Our findings support hypothesis may protect against adult cancer, even moderate levels.

参考文章(32)
K. M. Pirke, U. Schweiger, A. Broocks, B. Spyra, R. J. Tuschl, R. G. Laessle, Endocrine Studies in Female Athletes with and Without Menstrual Disturbances Springer, Berlin, Heidelberg. pp. 171- 178 ,(1989) , 10.1007/978-3-642-74631-4_18
Clarice R. Weinberg, Sholom Wacholder, The design and analysis of case-control studies with biased sampling. Biometrics. ,vol. 46, pp. 963- 975 ,(1990) , 10.2307/2532441
D. C. Cumming, Menstrual Disturbances Caused by Exercise Springer, Berlin, Heidelberg. pp. 150- 160 ,(1989) , 10.1007/978-3-642-74631-4_16
Chi-Ling Chen, Emily White, Kathleen E. Malone, Janet R. Daling, Leisure-time physical activity in relation to breast cancer among young women (Washington, United States). Cancer Causes & Control. ,vol. 8, pp. 77- 84 ,(1997) , 10.1023/A:1018439306604
Jennifer L. Kelsey, Breast Cancer Epidemiology: Summary and Future Directions Epidemiologic Reviews. ,vol. 15, pp. 256- 263 ,(1993) , 10.1093/OXFORDJOURNALS.EPIREV.A036112
Malcolm C. Pike, Darcy V. Spicer, Laila Dahmoush, Michael F. Press, Estrogens, Progestogens, Normal Breast Cell Proliferation, and Breast Cancer Risk Epidemiologic Reviews. ,vol. 15, pp. 17- 35 ,(1993) , 10.1093/OXFORDJOURNALS.EPIREV.A036102
James M. Robins, Sander Greenland, Identifiability and exchangeability for direct and indirect effects. Epidemiology. ,vol. 3, pp. 143- 155 ,(1992) , 10.1097/00001648-199203000-00013
Anne McTiernan, Exercise and Breast Cancer — Time to Get Moving? The New England Journal of Medicine. ,vol. 336, pp. 1311- 1312 ,(1997) , 10.1056/NEJM199705013361808
Yao-Hua Hu, Chisato Nagata, Hiroyuki Shimizu, Nobuyuki Kaneda, Yoshitomo Kashiki, Association of body mass index, physical activity, and reproductive histories with breast cancer: a case-control study in Gifu, Japan Breast Cancer Research and Treatment. ,vol. 43, pp. 65- 72 ,(1997) , 10.1023/A:1005745824388
R E Frisch, G Wyshak, N L Albright, T E Albright, I Schiff, K P Jones, J Witschi, E Shiang, E Koff, M Marguglio, Lower prevalence of breast cancer and cancers of the reproductive system among former college athletes compared to non-athletes. British Journal of Cancer. ,vol. 52, pp. 885- 891 ,(1985) , 10.1038/BJC.1985.273