The dynamics of error processing in the human brain as reflected by high-gamma activity in noninvasive and intracranial EEG.

摘要: Abstract Error detection in motor behavior is a fundamental cognitive function heavily relying on local cortical information processing. Neural activity the high-gamma frequency band (HGB) closely reflects such processing, but little known about its role error particularly healthy human brain. Here we characterize error-related response of brain based data obtained with noninvasive EEG optimized for HGB mapping 31 subjects (15 females, 16 males), and additional intracranial from 9 epilepsy patients (4 5 males). Our findings reveal multiscale picture global dynamics On level as reflected EEG, started an early component dominated by anterior regions, followed shift to parietal subsequent phase characterized sustained activity. This lasted more than 1 s after onset. cascade both transient responses involved even extended network, spanning beyond frontal regions insula hippocampus. appeared especially well suited investigate late, components response, possibly linked downstream functional stages learning behavioral adaptation. establish basic spatio-temporal properties neural correlate complementing traditional potential studies.