2-Thioether A2A receptor agonists

作者: Gloria Cristalli

DOI:

关键词:

摘要: 2-adenosine propargyl phenyl ether compositions having formula (I) and methods for using the as A2A receptor agonists to stimulate mammalian coronary vasodilatation therapeutic purposes of imaging heart.

参考文章(9)
Hideo Suehiro, Motonobu Ichino, Tokuro Nakamura, Kiyomi Kikugawa, S-substituted-2-thioadenosines ,(1975)
RYUJI MARUMOTO, YOSHIO YOSHIOKA, OSAMU MIYASHITA, SHUNSUKE SHIMA, KINICHI IMAI, KATSUYOSHI KAWAZOE, MIKIO HONJO, Synthesis and coronary vasodilating activity of 2-substituted adenosines. Chemical & Pharmaceutical Bulletin. ,vol. 23, pp. 759- 774 ,(1975) , 10.1248/CPB.23.759
Ahmad Hasan, Tahir Hussain, S. Jamal Mustafa, Prem C. Srivastava, 2-substituted thioadenine nucleoside and nucleotide analogues: synthesis and receptor subtype binding affinities (1). Bioconjugate Chemistry. ,vol. 5, pp. 364- 369 ,(1994) , 10.1021/BC00028A014
Bilha Fischer, Ana Chulkin, Jose L. Boyer, Kendall T. Harden, Fernand-Pierre Gendron, Adrien R. Beaudoin, Jeannie Chapal, Dominique Hillaire-Buys, Pierre Petit, 2-thioether 5'-O-(1-thiotriphosphate)adenosine derivatives as new insulin secretagogues acting through P2Y-Receptors. Journal of Medicinal Chemistry. ,vol. 42, pp. 3636- 3646 ,(1999) , 10.1021/JM990158Y
Bharat K. Trivedi, Robert F. Bruns, C2,N6-disubstituted adenosines: synthesis and structure-activity relationships. Journal of Medicinal Chemistry. ,vol. 32, pp. 1667- 1673 ,(1989) , 10.1021/JM00128A002
Maarten de Zwart, Regina Link, Jacobien K. von Frijtag Drabbe Kunzela, Gloria Cristalli, Kenneth A. Jacobson, Andrea Townsend-Nicholson, Ad P. IJzerman, A Functional Screening of Adenosine Analogues at the Adenosine A2BReceptor: A Search for Potent Agonists Nucleosides and Nucleotides. ,vol. 17, pp. 969- 985 ,(1998) , 10.1080/07328319808004215
Suzanne Elaine Keeling, George Blanch Ewan, Michael Gregson, Barry Edward Di Ayres, Richard Bell, AMINO PURINE-β-D-RIBOFURANURONAMIDE DERIVATIVES ,(1995)
Hideo Suehiro, Kazuhiro Iizuka, Motonobu Ichino, Tokuro Nakamura, Kiyomi Kikugawa, Leiko Sugata, S-substd 2-thioadenosines - as coronary vasodilators and blood platelet aggregation inhibitors ,(1973)
KIYOMI KIKUGAWA, HIDEO SUEHIRO, RYOBUN YANASE, AKIJI AOKI, Platelet Aggregation Inhibitors. IX. Chemical Transformation of Adenosine into 2-Thioadenosine Derivatives Chemical & Pharmaceutical Bulletin. ,vol. 25, pp. 1959- 1969 ,(1977) , 10.1248/CPB.25.1959