Purine derivative and antitumor agent using same

作者: Ichiro Koshimizu , Toshiyuki Matsuno , Kenichi Saitoh , Toshiaki Suzuki , Hideki Satoh

DOI:

关键词:

摘要: Disclosed are: a novel purine derivative, composition thereof, method for treating tumor using the and an antitumor agent derivative. Specifically disclosed is compound represented by formula (I), or pharmaceutically acceptable salt, solvate hydrate prodrug thereof.

参考文章(12)
Gloria Cristalli, 2-Thioether A2A receptor agonists ,(2001)
Paul Andrew Brough, Xavier Barril-Alonso, Martin Drysdale, Purine compounds as hsp90 protein inhibitors for the treatment of cancer ,(2006)
Haruhisa Ogita, o Sumitomo Pharmaceuticals Co. Ltd. Isobe, o Sumitomo Pharmaceuticals Co.Ltd. Fujita, o Sumitomo Pharmaceuticals Co. Ltd. Tobe, o Sumitomo Pharmaceuticals Co.Ltd. Takaku, o Sumitomo Pharmaceuticals Co.Ltd. Ogino, o Sumitomo Pharmaceuticals Co.Ltd. Kurimoto, Adenine compound and use thereof ,(2003)
Peter G. M. Wuts, Theodora W. Greene, Protective groups in organic synthesis ,(1981)
Alfonso R. Gennaro, Joseph P. Remington, Remington's pharmaceutical sciences Published in <b>1975</b> in Easton Pa) by Mack. ,(1985)
Ayumu Kurimoto, Hajime Kawakami, Tetsuhiro Ogino, Novel heterocyclic compounds ,(1998)
Sarah M Wignall, Nathanael S Gray, Young-Tae Chang, Lolita Juarez, Richard Jacob, Al Burlingame, Peter G Schultz, Rebecca Heald, Identification of a Novel Protein Regulating Microtubule Stability through a Chemical Approach Chemistry & Biology. ,vol. 11, pp. 135- 146 ,(2004) , 10.1016/J.CHEMBIOL.2003.12.019
Madhu AstraZeneca R D Boston Gowravaram, Hoan AstraZeneca R D Boston Huynh, Suzanne AstraZeneca R D Boston Stokes, Marta AstraZeneca R D Boston Cavero-Tomas, Haihong AstraZeneca R D Boston Ni, Substituted adenines and the uses thereof ,(2005)
Akira Amenomori, Toshihiko Tanaka, Akiko Tarao, Yuya Ono, Eiichirou Iwashita, Purine derivatives and medicaments comprising the same as active ingredient ,(1998)
Ichino Motonobu, Kawada Isako, Suehiro Hideo, Kikukawa Kiyomi, SYNTHESIS OF 99SUBSTITUTEDD22SUBSTITUTED THIOADENINES ,(1977)