Method of screening candidate compounds for susceptibility to biliary excretion by endogenous transport systems
作者： Kim L. R. Brouwer , Edward L. LeCluyse , Xingrong Liu
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摘要: A method of screening a candidate compound for susceptibility to biliary excretion. The includes the steps providing culture hepatocytes, having at least one bile canaliculus; exposing culture; and determining an amount in canaliculus, canaliculus indicating Optionally, hepatocytes is long-term sandwich configuration. particularly applicable multiple compounds single effort.
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