Postprandial sleep mechanics in Drosophila

作者: Keith R Murphy , Sonali A Deshpande , Maria E Yurgel , James P Quinn , Jennifer L Weissbach

DOI: 10.7554/ELIFE.19334

关键词:

摘要: Many of us have experienced feelings sleepiness after a large meal. However, there is little scientific evidence that this “food coma” effect real. If it is, may vary between individuals, or depend on the type food consumed. This variability makes difficult to study causes post-meal sleepiness. Murphy et al. now developed system can measure fruit fly sleep and feeding behavior at same time. Recordings using reveal meal, flies more for short period before returning normal state wakefulness. The lasts around 20-40 minutes, with ate generally sleeping more. Further investigation revealed salty protein-rich foods promote sleep, whereas sugary do not. By genetic tools turn off neurons in brain, identified number brain circuits play role controlling Some these respond specifically consumption protein. Others are sensitive fly’s internal clock, reducing only dusk. Thus, be regulated different ways. Future experiments needed explore genes enable meal size protein salt content drive sleep. In nature, likely vulnerable animals. another challenge will uncover why important. Does boost digestion? Or might help animals form memories about source, making easier find similar future?

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