Charge transfer in DNA : from mechanism to application

摘要: Foreword. Preface. List of Contributors. 1 Principles and Mechanisms Photoinduced Charge Injection, Transport, Trapping in DNA (Hans-Achim Wagenknecht). 1.1 Introduction. 1.2 Synthetic DNA-Donor-Acceptor Systems. 1.3 Oxidative Hole Transfer vs. Reductive Electron DNA. 1.4 Hopping 1.5 1.6 Conclusions. 2 Sequence-dependent Dynamics: The Regulator DNA-mediated Transport (Melanie A. O'Neill Jacqueline K. Barton). 2.1 2.2 Experimental Approaches to Studies Over Varied Energetic Time Regimes. 2.3 Understanding the Fundamental Parameters Governing Transport. 2.4 A Mechanistic Model for Transport: Beyond Superexchange Incoherent Hopping. 2.5 Biology. 2.6 Conclusions Outlook. 3 Excess Probed with Flavin- Thymine Dimer-modified Oligonucleotides (Thomas Carell Martin von Meltzer). 3.1 3.2 Transfer-driven Repair by Photolyases. 3.3 3.4 Catalytic Electron? Or, Can One More Than Dimer Lesion? 3.5 Future Directions. 4 Dynamics Photoinitiated Injection Duplex (Frederick D. Lewis Michael R. Wasielewski). 4.1 4.2 Hairpin Synthesis, Structure, Energetics. 4.3 Injection. 4.4 4.5 5 Spectroscopic Investigation via Adenine (Kiyohiko Kawai Tetsuro Majima). 5.1 5.2 Kinetics 5.3 Long-lived, Charge-separated State 5.4 Effect on Photosensitized Damage. 5.5 6 Chemical Probing (Steven E. Rokita Takeo Ito). 6.1 6.2 Reaction-based Method Characterize Transfer. 6.3 Structural Dependence BrU Reduction 6.4 General Prospects. 7 Approach Modulating Through (Chikara Dohno Isao Saito). 7.1 7.2 Hole-injection 7.3 Modulation Efficiency. 7.4 Trapping. 7.5 8 (Vladimir Shafirovich Nicholas Geacintov). 8.1 8.2 Two-photon Ionization 2-Aminopurine 8.3 Oxidation Guanine Residues Radicals 8.4 End Products Oxidation. 8.5 Concluding Remarks. 9 Wagenknecht Torsten Fiebig). 9.1 9.2 Pyrene-modified Nucleosides as Systems 9.3 Pyrene an Injector a Probe Base 9.4 Phenothiazine-modified 9.5 Flexibility Py dU-Modified 9.5.2 Spectral Properties, Dynamics, Information. 9.6 Ethidium Artificial Donor 9.7 Subject Index.