CHAPTER 10 – Biomarkers and Biological Indicators of Change

摘要: A biomarker or biological indicator is a characteristic that measured and evaluated as marker of normal processes, pathogenic responses to an intervention. In theory, almost any measurement reflects change in biochemical process, structure, function can be used biomarker. addition, exogenous compound that, result ingestion, inhalation, absorption, tissues body fluids also considered Biomarkers classified broadly into markers exposure, effect, susceptibility have numerous applications nutrition. This chapter presents the basic concepts key issues related various uses biomarkers Identification use continuously evolving with growing understanding biologic processes improved sensitivity laboratory assays. Biochemical measurements may collected provide objective evidence dietary pattern, such overall fruit vegetable consumption, validate assessment instruments self-reported data. Another possible purpose for obtaining these measures establish link between nutritional factor physiological when concentration micronutrient constituent peripheral tissue.