Potential synergism of natural products in the treatment of cancer.

摘要: Cancer is the second leading cause of death worldwide. There thus increased interest in alternative treatment modalities that include chemotherapy, hormonal supplements, surgery, radiation therapy, complementary or alterative medicine, used alone combination. Therefore patients who are subjected to combination treatments such as supplements medicine face considerable risk drug-drug interactions. The administration herbal drugs by without a physician's prior counseling increasing globally and there possibility herb-drug interactions too. Herbal extracts themselves contain active constituents, which interact within also between other prescribed pharmaceutical either enhance (synergize) decrease (antagonize) therapeutic effect. This review focuses on number reports interactions, their mechanism action with special emphasis dietetic phytochemicals quercetin, genistein, curcumin catechins. All tend increase effect blocking one more targets signal transduction pathway, bioavailability drug or, stabilizing system.