作者: Lorenzo Zaffiri , Jared Gardner , Luis H. Toledo-Pereyra
DOI: 10.3109/08941939.2012.664099
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摘要: ABSTRACTInfections have represented for a long time the leading cause of death in humans. During 19th century, pneumonia, tuberculosis, diarrhea and diphtheria were considered main causes children adults. Only late century did it become possible to correlate existence microscopic pathogens with development various diseases. Within few years introduction antiseptic procedures had begun reduce mortality due postsurgical infections. Sanitation hygiene played significant role reduction several infectious The first compounds antimicrobial activity succeeded conquering many diseases.In this review we analyzed, from historical perspective, antibiotics circumstances that led their discovery. compound was introduced 1911 by Erlich. He focused his research on discovery “magic bullet” t...