Interactions between the Pharmaceutical Active Ingredient Ionic Liquid and Small Biomolecules: A Mini Review

Katharina Bica, Christiaan Rijksen, Mark Nieuwenhuyzen, Robin D. Rogers, In search of pure liquid salt forms of aspirin: ionic liquid approaches with acetylsalicylic acid and salicylic acid. Physical Chemistry Chemical Physics. ,vol. 12, pp. 2011- 2017 ,(2010) , 10.1039/B923855G

Paula C. A. G. Pinto, Diogo M. G. P. Ribeiro, Ana M. O. Azevedo, Vanessa Dela Justina, E. Cunha, K. Bica, M. Vasiloiu, Salette Reis, M. Lúcia M. F. S. Saraiva, Active pharmaceutical ingredients based on salicylate ionic liquids: insights into the evaluation of pharmaceutical profiles New Journal of Chemistry. ,vol. 37, pp. 4095- 4102 ,(2013) , 10.1039/C3NJ00731F

Kasthuraiah Maddali, Vineet Kumar, Christophe Marchand, Yves Pommier, Sanjay V. Malhotra, Biological evaluation of imidazolium- and ammonium-based salts as HIV-1 integrase inhibitors Med. Chem. Commun.. ,vol. 2, pp. 143- 150 ,(2011) , 10.1039/C0MD00201A

Jelena Stoimenovski, Douglas R. MacFarlane, Katharina Bica, Robin D. Rogers, Crystalline vs. Ionic Liquid Salt Forms of Active Pharmaceutical Ingredients: A Position Paper Pharmaceutical Research. ,vol. 27, pp. 521- 526 ,(2010) , 10.1007/S11095-009-0030-0

Juliusz Pernak, Kinga Sobaszkiewicz, Ilona Mirska, Anti-microbial activities of ionic liquids Green Chemistry. ,vol. 5, pp. 52- 56 ,(2003) , 10.1039/B207543C

Hemayat Shekaari, Mohammed Taghi Zafarani-Moattar, Seyyedeh Narjes Mirheydari, Thermodynamic properties of 1-butyl-3-methylimidazolium salicylate as an active pharmaceutical ingredient ionic liquid (API-IL) in aqueous solutions of glycine and L-alanine at T = (288.15–318.15) K Thermochimica Acta. ,vol. 637, pp. 51- 68 ,(2016) , 10.1016/J.TCA.2016.05.013

Hemayat Shekaari, Mohammed Taghi Zafarani-Moattar, Seyyedeh Narjes Mirheydari, Effect of 1-Butyl-3-methylimidazolium Ibuprofenate as an Active Pharmaceutical Ingredient Ionic Liquid (API-IL) on the Thermodynamic Properties of Glycine and l -Alanine in Aqueous Solutions at Different Temperatures Journal of Solution Chemistry. ,vol. 45, pp. 624- 663 ,(2016) , 10.1007/S10953-016-0462-1

Hemayat Shekaari, Mohammed Taghi Zafarani-Moattar, Seyyedeh Narjes Mirheydari, Conductometric analysis of 1-butyl-3-methylimidazolium ibuprofenate as an active pharmaceutical ingredient ionic liquid (API-IL) in the aqueous amino acids solutions The Journal of Chemical Thermodynamics. ,vol. 103, pp. 165- 175 ,(2016) , 10.1016/J.JCT.2016.07.047

Zhenning Yan, Wenwen Chu, Shuangxia Shen, Limin Ma, Volumetric and UV Absorption Studies on Interactions of an Active Pharmaceutical Ingredient Ionic Liquid (API-IL) Domiphen l -Proline with Amino Acids and Glycyl Dipeptides in Aqueous Solution at T = (293.15–308.15) K Journal of Solution Chemistry. ,vol. 46, pp. 1658- 1679 ,(2017) , 10.1007/S10953-017-0671-2

Zhenning Yan, Limin Ma, Shuangxia Shen, Jinpeng Li, Studies on the interactions of some small biomolecules with antibacterial drug benzethonium chloride and its active pharmaceutical ingredient ionic liquid (API-IL) benzethonium L-proline at varying temperatures Journal of Molecular Liquids. ,vol. 255, pp. 530- 540 ,(2018) , 10.1016/J.MOLLIQ.2018.02.007