Effects of benzimidazole on the oxygen-induced biosynthesis of hemoproteins in yeast.
作者： Andre A. Sels , Anne-Marie Verhulst
DOI: 10.1111/J.1432-1033.1971.TB01294.X
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摘要: 1 Benzimidazole almost completely inhibited respiratory adaptation of yeast under conditions where total protein synthesis was only partially inhibited. 2 The effects benzimidazole on the individual hemoproteins were examined. The production enzymatically active cytochrome oxidase totally blocked; this accounts for interruption adaptation. biosynthesis NADH (and succinate): c oxidoreductase segments, which include cytochromes b and c1, inhibited. induced iso-1-cytochrome displayed a singular insensitivity to action drug. mechanism inhibition by appears be different from that cycloheximide chloramphenicol.
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