The role of ascorbic acid in the biosynthesis of collagen. I. Ascorbic acid requirement by embryonic chick tibia in tissue culture.
作者： John J. Jeffrey , G.R. Martin
DOI: 10.1016/0304-4165(66)90116-4
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摘要: Abstract Embryonic chick tibias, when incubated in a chemically defined medium, grow and synthesize collagen for several days. The tissues display marked dependence upon the presence of L -ascorbic acid culture medium normal growth. Deletion ascorbic reduces synthesis by bones after first 2 days culture. A less drastic reduction other proteins, DNA RNA, was also observed. rate these substances rapidly restored addition acid.
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sci-hub.se 参考文章(10)
Chozo Mitoma, Thomas E. Smith, Studies on the Role of Ascorbic Acid in Collagen Synthesis Journal of Biological Chemistry. ,vol. 235, pp. 426- 428 ,(1960) , 10.1016/S0021-9258(18)69540-7
Darwin J. Prockop, Beverly Peterkofsky, Sidney Udenfriend, Studies on the intracellular localization of collagen synthesis in the intact chick embryo. Journal of Biological Chemistry. ,vol. 237, pp. 1581- 1584 ,(1962) , 10.1016/S0021-9258(19)83743-2
Francis McDonald, George Hass, Studies of collagen: I. The production of collagen in vitro under variable experimental conditions. American Journal of Pathology. ,vol. 16, pp. 525- 548 ,(1940)
Bernard S. Gould, J. Frederick Woessner, BIOSYNTHESIS OF COLLAGEN Journal of Biological Chemistry. ,vol. 226, pp. 289- 300 ,(1957) , 10.1016/S0021-9258(18)64830-6
Darwin J. Prockop, Sidney Udenfriend, A specific method for the analysis of hydroxyproline in tissues and urine. Analytical Biochemistry. ,vol. 1, pp. 228- 239 ,(1960) , 10.1016/0003-2697(60)90050-6
I. B. Chatterjee, N. C. Kar, N. C. Ghosh, B. C. Guha, ASPECTS OF ASCORBIC ACID BIOSYNTHESIS IN ANIMALS* Annals of the New York Academy of Sciences. ,vol. 92, pp. 36- 56 ,(1961) , 10.1111/J.1749-6632.1961.TB46105.X
A. Jeney, E. Törő, Die Wirkung der Ascorbinsäure auf die Faserbildung in Fibroblastkulturen Virchows Archiv. ,vol. 298, pp. 87- 97 ,(1936) , 10.1007/BF01888002
HOWARD GREEN, BURTON GOLDBERG, KINETICS OF COLLAGEN SYNTHESIS BY ESTABLISHED MAMMALIAN CELL LINES. Nature. ,vol. 200, pp. 1097- 1098 ,(1963) , 10.1038/2001097A0
J. Frederick Woessner, Bernard S. Gould, Collagen biosynthesis; tissue culture experiments to ascertain the role of ascorbic acid in collagen formation Journal of Cell Biology. ,vol. 3, pp. 685- 695 ,(1957) , 10.1083/JCB.3.5.685
Henry Tauber, Methods of Enzymology. Journal of the American Chemical Society. ,vol. 78, pp. 3234- 3234 ,(1956) , 10.1021/JA01594A086