Viral mimicry of cytokines, chemokines and their receptors

作者: Antonio Alcami

DOI: 10.1038/NRI980

关键词:

摘要: Viruses have evolved elegant mechanisms to evade detection and destruction by the host immune system. One of evasion strategies that been adopted large DNA viruses is encode homologues cytokines, chemokines their receptors — molecules a crucial role in control response. captured genes or target specific pathways, so viral genomes can be regarded as repositories important information about processes, offering us view The study immunomodulatory proteins might help uncover new human immunity, characterization will increase our understanding not only pathogenesis, but also normal mechanisms. Moreover, indicate modulation therapeutic potential.

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