作者: Martha Shaw , Donald W. Black , Jeff Allen , Kelsie T. Forbush
DOI: 10.1097/WNF.0B013E31803D357F
关键词:
摘要: Background: The effectiveness and tolerability of escitalopram was tested in the treatment pathological gambling (PG). Method: Nondepressed outpatients with Diagnostic Statistical Manual Mental Disorders, Fourth Edition PG received flexibly dosed a prospective, 10-week, open-label trial after 2-week observation period. Subjects were evaluated at baseline intervals for assessment behavior, mood symptoms, adverse experiences. primary efficacy measure Yale-Brown Obsessive-Compulsive Scale modified PG. Secondary measures included Clinical Global Impression (CGI) Improvement Severity Scales, patient self-rated global rating, Sheehan Disability Scale, Timeline Follow Back. Results: Nineteen subjects (12 men 7 women) had least 1 postbaseline visit analysis; 16 (84%) completed protocoL Significant improvement found all measures, including PG, both CGI scale, Back, Attention-Deficit/Hyperactivity Disorder Checklist, Hamilton Depression Rating 3 subscales. Fourteen (73.7%) considered responders (ie, achieved "much" or "very much" on CGI). Few experiences reported. Conclusion: results suggest that is well tolerated may be effective