Respiratory symptoms and cross-shift lung function in relation to cotton dust and endotoxin exposure in textile workers in Nepal: a cross-sectional study

摘要: Objectives: Inhalation of a cotton-based particulates has previously been associated with respiratory symptoms and impaired lung function. This study investigates the health Nepalese textile workers in relation to dust endotoxin exposure. Methods: A total 938 individuals from four sectors (garment, carpet, weaving recycling) industry Kathmandu, Nepal completed questionnaire performed spirometry. subset (n=384) cross-shift Personal exposure inhalable airborne was measured during full shift for 114 workers. Results: The overall prevalence persistent cough, phlegm, wheeze ever, breathlessness ever chest tightness 8.5%, 12.5%, 3.2%, 6.5% 12.3%, respectively. Symptoms were most common among recyclers least garment Exposure significantly predicted cough tightness. did not have any independent predictive effect. Significant reduction forced expiratory volume 1 s (FEV1) vital capacity (FVC) found (p<0.001 both) being largest FEV1 (−143 mL), (−38 mL; p=0.012). FEV1. Conclusions: is first investigate cotton association between reporting across-shift decrement FVC indicates that improved control measures should be instituted, particularly recycling carpet sectors. possible role other biologically active agents beyond further explored.