Attempt to suppress excessive growth in girls by estrogen treatment: statistical evaluation.

摘要: ABSTRACT. Fourteen healthy girls, aged 9.5–14.4 years, whose average predicted adult height was 70 inches, were given estrogens for an of 23 months in attempt to reduce height. Seven 69.3 attained observed 68.9 inches. The difference between and is not statistically significant. In 7 girls who have yet height, heights before after treatment identical at 71.4 Estrogen accelerated the rate skeletal maturation 1.26 years per chronologic year. (The normal 0.93.) Since unchanged, estrogen must increased linear growth simultaneously proportionately. use valid samples urged avoid misinterpreting individual variations as therapeutic results.