Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders
作者： Yong A. Yu , Phil Hill , Aladara A. Szalay , Jochen Harald Stritzker
DOI:
关键词:
摘要: Described herein are methods for detecting a microorganism or cell in subject and detecting, imaging diagnosing site, disease, disorder condition using microorganisms cells. Also described which use cells treating condition. Such sites, diseases disorders include sites of proliferation, proliferative conditions, neoplasms, tumors, neoplastic wounds inflammation. Further the compositions, combinations kits, including diagnostic pharmaceutical containing cell. Microorganisms those that bind, sequester accumulate metal, such as provide metal acquisition, transport, storage and/or metabolism. Additional therapy agents also described.
google.je参考文章(442)
Heung-Chae Jung, Jean-Michel Lebeault, Jae-Gu Pan, Surface display of Zymomonas mobilis levansucrase by using the ice-nucleation protein of Pseudomonas syringae Nature Biotechnology. ,vol. 16, pp. 576- 580 ,(1998) , 10.1038/NBT0698-576
T. Itoh, J. Tomizawa, Formation of an RNA primer for initiation of replication of ColE1 DNA by ribonuclease H Proceedings of the National Academy of Sciences of the United States of America. ,vol. 77, pp. 2450- 2454 ,(1980) , 10.1073/PNAS.77.5.2450
Wadih Arap, Renata Pasqualini, Erkki Ruoslahti, Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model Science. ,vol. 279, pp. 377- 380 ,(1998) , 10.1126/SCIENCE.279.5349.377
John Condeelis, Jeffrey E. Segall, Intravital imaging of cell movement in tumours Nature Reviews Cancer. ,vol. 3, pp. 921- 930 ,(2003) , 10.1038/NRC1231
Prem Ponka, Herbert M Schulman, Robert C Woodworth, Goetz W Richter, Iron Transport and Storage ,(1990)
N. Aziz, H. N. Munro, Iron regulates ferritin mRNA translation through a segment of its 5' untranslated region. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 84, pp. 8478- 8482 ,(1987) , 10.1073/PNAS.84.23.8478
Ricardo Pardal, Michael F. Clarke, Sean J. Morrison, Applying the principles of stem-cell biology to cancer Nature Reviews Cancer. ,vol. 3, pp. 895- 902 ,(2003) , 10.1038/NRC1232
Luis E. N. Quadri, Assembly of aryl-capped siderophores by modular peptide synthetases and polyketide synthases. Molecular Microbiology. ,vol. 37, pp. 1- 12 ,(2000) , 10.1046/J.1365-2958.2000.01941.X
Xi Li, Geng-Feng Fu, Yan-Rong Fan, Wen-Hua Liu, Xin-Juan Liu, Jian-Jun Wang, Gen-Xing Xu, Bifidobacterium adolescentis as a delivery system of endostatin for cancer gene therapy: selective inhibitor of angiogenesis and hypoxic tumor growth. Cancer Gene Therapy. ,vol. 10, pp. 105- 111 ,(2003) , 10.1038/SJ.CGT.7700530
Mark A Rizzo, Gerald H Springer, Butch Granada, David W Piston, An improved cyan fluorescent protein variant useful for FRET. Nature Biotechnology. ,vol. 22, pp. 445- 449 ,(2004) , 10.1038/NBT945