KOH-mediated transition metal-free synthesis of imines from alcohols and amines
作者： Jian Xu , Rongqiang Zhuang , Lingling Bao , Guo Tang , Yufen Zhao
DOI: 10.1039/C2GC35714C
关键词:
摘要: The various imines were prepared from alcohols and amines in moderate to good yields under an air atmosphere promoted by KOH, eliminating the need for toxic transition metal catalysts. Due its simplicity, this protocol will have wide application synthesis.
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K. C. Nicolaou, Casey J. N. Mathison, Tamsyn Montagnon, New Reactions of IBX: Oxidation of Nitrogen- and Sulfur-Containing Substrates To Afford Useful Synthetic Intermediates Angewandte Chemie International Edition. ,vol. 42, pp. 4077- 4082 ,(2003) , 10.1002/ANIE.200352076
Lei Shi, Hui-Ming Ge, Shu-Hua Tan, Huan-Qiu Li, Yong-Chun Song, Hai-Liang Zhu, Ren-Xiang Tan, Synthesis and antimicrobial activities of Schiff bases derived from 5-chloro-salicylaldehyde. European Journal of Medicinal Chemistry. ,vol. 42, pp. 558- 564 ,(2007) , 10.1016/J.EJMECH.2006.11.010
Zong-Ying Liu, Yue-Ming Wang, Zhuo-Rong Li, Jian-Dong Jiang, David W. Boykin, Synthesis and anticancer activity of novel 3,4-diarylthiazol-2(3H)-ones (imines) Bioorganic & Medicinal Chemistry Letters. ,vol. 19, pp. 5661- 5664 ,(2009) , 10.1016/J.BMCL.2009.08.025
Min Serk Kwon, Sungjin Kim, Sungho Park, William Bosco, Ravi Kumar Chidrala, Jaiwook Park, One-pot synthesis of imines and secondary amines by Pd-catalyzed coupling of benzyl alcohols and primary amines. Journal of Organic Chemistry. ,vol. 74, pp. 2877- 2879 ,(2009) , 10.1021/JO8026609
Guo Tang, Chien-Hong Cheng, Synthesis of α‐Hydroxy Carboxylic Acids via a Nickel(II)‐ Catalyzed Hydrogen Transfer Process Advanced Synthesis & Catalysis. ,vol. 353, pp. 1918- 1922 ,(2011) , 10.1002/ADSC.201100241
Robert H. Crabtree, Introduction to Selective Functionalization of C−H Bonds Chemical Reviews. ,vol. 110, pp. 575- 575 ,(2010) , 10.1021/CR900388D
Stewart E. Hazlet, Dale A. Stauffer, Crossed Cannizzaro Reactions Journal of Organic Chemistry. ,vol. 27, pp. 2021- 2024 ,(1962) , 10.1021/JO01053A025
Qiang Kang, Yugen Zhang, Copper-catalyzed highly efficient aerobic oxidative synthesis of imines from alcohols and amines Green Chemistry. ,vol. 14, pp. 1016- 1019 ,(2012) , 10.1039/C2GC16548A
Nobuyuki Uematsu, Akio Fujii, Shohei Hashiguchi, Takao Ikariya, Ryoji Noyori, Asymmetric Transfer Hydrogenation of Imines Journal of the American Chemical Society. ,vol. 118, pp. 4916- 4917 ,(1996) , 10.1021/JA960364K
R. K. Thalji, K. A. Ahrendt, R. G. Bergman, J. A. Ellman, Annulation of Aromatic Imines via Directed C−H Activation with Wilkinson's Catalyst Journal of the American Chemical Society. ,vol. 123, pp. 9692- 9693 ,(2001) , 10.1021/JA016642J