Medium-term outcome of endoluminal gastroplication with the EndoCinch device in children.

摘要: Objective: Endoluminal gastroplication (EG) is emerging as a minimally invasive procedure for the treatment of gastroesophageal reflux disease (GERD). The aim this study to evaluate medium-term outcomes after EG in pediatric patient population. Patients and Methods: Seventeen children with median age 12.4 years (range 6.1-15.9 years) GERD underwent using flexible endoscopic sewing device (EndoCinch) over period 3 years. Three plications were placed gastric tissue below lower esophageal sphincter. Drug dose requirement, pH measurements, symptom severity frequency, validated Quality Life Reflux Dyspepsia (QOLRAD) scores compared before 1 EG. Statistical analysis was performed Wilcoxon rank-sum test P < 0.05 threshold significance. Results: All patients showed an immediate posttreatment improvement severity, quality life scores. Completed 1- 3-year data obtained from 16 patients. Four cases (25%) required repeat result recurrence symptoms 2 24 months. Fourteen (88%) at year 9 (56%) remained without need any antireflux medication. A sustained heartburn (P = 0.004), regurgitation 0.017), vomiting 0.018) seen total QOLRAD score (maximum 175) improved 87 69-142) 156 111 -175) (P<0.0001) 153.5 55-174) 0.002). Conclusions: effective safe children. It viable option refractory or dependent on medications.