B-type natriuretic peptide and prognosis in heart failure patients with preserved and reduced ejection fraction.

摘要: Objectives This study sought to determine the prognostic value of B-type natriuretic peptide (BNP) in patients with heart failure preserved ejection fraction (HFPEF), comparison data HF reduced left ventricular (LV) EF (≤40%). Background Management HFPEF is difficult. BNP a useful biomarker LVEF, but are scarce. Methods In this study, 615 mild moderate (mean age 70 years, LVEF 33%) were followed for 18 months. concentrations measured at baseline and related primary outcome, that is, composite all-cause mortality hospitalization, alone. The population was divided quintiles, according compared those HFPEF. Results There 257 (42%) who had endpoint 171 (28%) died. levels significantly higher than (p Conclusions lower given level, prognosis as poor LVEF.