The promise of metabolic phenotyping in gastroenterology and hepatology

作者: Elaine Holmes , Anisha Wijeyesekera , Simon D. Taylor-Robinson , Jeremy K. Nicholson

DOI: 10.1038/NRGASTRO.2015.114

关键词:

摘要: Disease risk and treatment response are determined, at the individual level, by a complex history of genetic and environmental interactions, including those with our endogenous microbiomes. Personalized health care requires a deep understanding of patient biology that can now be measured using a range of'-omics' technologies. Patient stratification involves the identification of genetic and/or phenotypic disease subclasses that require different therapeutic strategies. Stratified medicine approaches to disease diagnosis …

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