摘要: Recent advances in the extent of knowledge regarding interindividual genetic variation drug treatment targets and metabolizing enzymes has resulted studies designed to assess contribution variability response a range diseases. This review describes current state key airway important asthma. Whilst genes coding for some contain little polymorphic (e.g. muscarinic M2 M3 receptors) other whose products are asthma extensive variation. The best examples latter β2-adrenoceptor 5-lipoxygenase genes. Genetic both these may account part response. Finally, number within airways remain be adequately screened
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