Tumor cell agglutination and not solely cytokine release as mechanism of adverse reactions during anti-CD20 monoclonal antibody (IDEC-C2B8, rituximab) treatment.
作者： Volker Kunzmann , Thomas Ruediger , Michael Hallek , Hans-Konrad Mueller-Hermelink , Martin Wilhelm
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摘要: The chimeric monoclonal anti-CD20 antibody has been widely used for the treatment of relapsed or refractory low-grade B-cell non-Hodgkin lymphoma (NHL). However, in patients with a high number tumor cells blood, severe infusion-related toxicities have reported.[1][1] On basis
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