Echinococcus multilocularis Infection: Immunology and Immunodiagnosis

作者: B. Gottstein

DOI: 10.1016/S0065-308X(08)60024-X

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摘要: Publisher Summary Echinococcus multilocularis was definitively established as an independent species by Vogel's exact morphological and biological investigations, including the completion of life cycle parasite in experimentally infected hosts. The natural E. is uniform, although host assemblages universally differ accordance with faunal changes southwards from Arctic. This fact principal determinant prevalence distribution parasite. Attempts to delineate three approximate geographical ranges have been made but distributional data are incomplete. Nevertheless, seems be uniquely restricted northern hemisphere. Alveolar echinococcosis (AE) humans biologically comparable disease intermediate primary localization metacestodes (larvae) (as well hosts) almost exclusively liver. Local extension lesion metastatic formation lungs, brain, other organs can follow. chapter presents immunological aspect also discusses various diagnostic techniques. New developments diagnosis vaccination against discussed, major crucial remains concentrated on identification antigens protect

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