Telomerase activity: a marker to distinguish follicular thyroid adenoma from carcinoma.
作者： William H. Westra , Christopher B. Umbricht , Robert Udelsman , Saraswati Sukumar , Martha A. Zeiger
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摘要: The inability to distinguish microinvasive follicular thyroid cancer from benign tumors preoperatively presents an important surgical dilemma. We examined 44 and found telomerase activity in all 11 carcinomas 8 of 33 tumors. It was undetectable 22 normal tissues adjacent the Telomerase may thus provide a diagnostic marker distinguishing malignant ability identify invasive could avert over 14,000 thyroidectomies annually United States, thereby significantly decreasing morbidity health care costs.
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