The maintenance of chromosome structure: positioning and functioning of SMC complexes
作者： Kristian Jeppsson , Takaharu Kanno , Katsuhiko Shirahige , Camilla Sjögren
DOI: 10.1038/NRM3857
关键词:
摘要: Structural maintenance of chromosomes (SMC) complexes, which in eukaryotic cells include cohesin, condensin and the Smc5/6 complex, are central regulators chromosome dynamics control sister chromatid cohesion, condensation, DNA replication, repair transcription. Even though molecular mechanisms that lead to this large range functions still unclear, it has been established complexes execute their through association with chromosomal DNA. A set data also indicates SMC work as intermolecular intramolecular linkers When combining these insights results from ongoing analyses binding, how interaction influences structure chromosomes, a picture carry out many starts emerge.
nature.com
sci-hub.se 参考文章(168)
Tomoyuki Tanaka, Jörg Fuchs, Josef Loidl, Kim Nasmyth, Cohesin ensures bipolar attachment of microtubules to sister centromeres and resists their precocious separation. Nature Cell Biology. ,vol. 2, pp. 492- 499 ,(2000) , 10.1038/35019529
Yuki Katou, Kiyofumi Kaneshiro, Hiroyuki Aburatani, Katsuhiko Shirahige, Genomic Approach for the Understanding of Dynamic Aspect of Chromosome Behavior DNA Repair, Part B. ,vol. 409, pp. 389- 410 ,(2006) , 10.1016/S0076-6879(05)09023-3
X. Zhao, G. Blobel, A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 102, pp. 4777- 4782 ,(2005) , 10.1073/PNAS.0500537102
David C. Amberg, Daniel Burke, Jeffrey N. Strathern, Methods in yeast genetics : a Cold Spring Harbor Laboratory course manual Cold Spring Harbor Laboratory Press. ,(2005)
Frank Uhlmann, Friedrich Lottspeich, Kim Nasmyth, Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1 Nature. ,vol. 400, pp. 37- 42 ,(1999) , 10.1038/21831
B J Meyer, D R Hsu, The dpy-30 gene encodes an essential component of the Caenorhabditis elegans dosage compensation machinery. Genetics. ,vol. 137, pp. 999- 1018 ,(1994) , 10.1093/GENETICS/137.4.999
Vincent Guacci, Douglas Koshland, Alexander Strunnikov, A Direct Link between Sister Chromatid Cohesion and Chromosome Condensation Revealed through the Analysis of MCD1 in S. cerevisiae Cell. ,vol. 91, pp. 47- 57 ,(1997) , 10.1016/S0092-8674(01)80008-8
Antonio Tedeschi, Gordana Wutz, Sébastien Huet, Markus Jaritz, Annelie Wuensche, Erika Schirghuber, Iain Finley Davidson, Wen Tang, David A. Cisneros, Venugopal Bhaskara, Tomoko Nishiyama, Alipasha Vaziri, Anton Wutz, Jan Ellenberg, Jan-Michael Peters, Wapl is an essential regulator of chromatin structure and chromosome segregation. Nature. ,vol. 501, pp. 564- 568 ,(2013) , 10.1038/NATURE12471
Karl-Peter Hopfner, Annette Karcher, David S. Shin, Lisa Craig, L.Matthew Arthur, James P. Carney, John A. Tainer, Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily. Cell. ,vol. 101, pp. 789- 800 ,(2000) , 10.1016/S0092-8674(00)80890-9
Theresa Hartman, Kristen Stead, Douglas Koshland, Vincent Guacci, Pds5p Is an Essential Chromosomal Protein Required for Both Sister Chromatid Cohesion and Condensation in Saccharomyces cerevisiae Journal of Cell Biology. ,vol. 151, pp. 613- 626 ,(2000) , 10.1083/JCB.151.3.613